SENDMAIL.py

import sys
from email.mime.text import MIMEText
from subprocess import Popen, PIPE

msg = MIMEText("Here is the body of my message")
msg["From"] = "[email protected]"
msg["To"] = "[email protected]"
msg["Subject"] = "This is the subject."
p = Popen(["/usr/sbin/sendmail", "-t", "-oi"], stdin=PIPE)
# Both Python 2.X and 3.X
p.communicate(msg.as_bytes() if sys.version_info >= (3,0) else msg.as_string()) 

# Python 2.X
p.communicate(msg.as_string())

# Python 3.X
p.communicate(msg.as_bytes())